High sugar intake = low dopamine release in the insulin resistant = model for addiction?

http://www.sciencedaily.com/releases/2013/06/130610223722.htm

For those with poor insulin sensitivity and raised blood glucose levels (hello type 2 diabetics) a sugary drink resulted in a lower-than-normal release of the chemical dopamine in... the
nucleus accumbens, where much of the brain's reward circuitry is located.

 After patients drank the sugary glucose, those who were insulin-resistant and had signs of disorderly eating were found to have remarkably lower natural dopamine release in response to glucose ingestion when compared with the insulin-sensitive control subjects.

"Animal studies indicated that increased insulin resistance precedes the lack of control associated with pathological overeating," said Wang. "They also showed that sugar ingestion releases dopamine in brain regions associated with reward. However, the central mechanism that contributes to insulin resistance, pathological eating and weight gain is unknown."